As RNA expression of CD33, CD123, CLL1, TIM3, CD244 and CD7 was similar in bone marrow of AML patients at initial diagnosis and complete remission (Supplemental Figure 8, Supplemental Table 4), we next evaluated the differential protein expression on AML bulk cells and LSC in comparison with healthy donor-derived hematopoietic stem/progenitor cells (HSPC/HSC), granulocytes, monocytes and lymphocytes (representative measurements in Fig. 2a; gating in Supplemental Fig. 1A). Here, CD244 is linked to acute myeloid leukemia.