Some predisposing variants are associated with specific types of cancer and sensitivity to specific controllable factors; for instance, a variant in the BAP1 gene is predisposing to a small group of cancers, including mesothelioma (Murali et al. 2013) and greater cancer risk from exposure to asbestos (Testa et al. 2011) and other environmental carcinogens (Bononi et al. 2017). Here, BAP1 is linked to cancer.