Kim et al. reported that fatty acid binding protein 4, S100 calcium binding protein A8/9, SH3 domain containing 1, α-2-HS-glycoprotein, and complement component 1, q subcomponent, A chain were up-regulated, while perilipin 1 and 4, carnitine palmitoyltransferase 2, acyl-CoA dehydrogenase, long chain, and acyl-CoA dehydrogenase, C-4 to C-12 straight chain were down-regulated in visceral adipose tissue of subjects with type 2 diabetes than in visceral adipose tissue of those with normal glucose tolerances. This evidence concerns the gene PLIN1 and type 2 diabetes mellitus.