In patients living with HIV whose CD4 count is <200, the newly available urine Lipoarabinomannan (LAM) test is a useful adjunct to the diagnosis of TB with a positive predictive value of 88.5% and a negative predictive value of 87.1% for all TB when used alone.43 Therefore, it is not specific for STB but can be a useful adjunct to diagnosis, specifically in patients whose CD4 count is < 200. This evidence concerns the gene CD4 and tuberculosis.