BRAF and neoplasm: We observed a non-significant association of histology with age at diagnosis (>65 versus ≤60), grade, microsatellite instability (MSI) status, lymphatic invasion (LI), and BRAF V600E mutation; a moderately significant association with stage, sex, and age at diagnosis between 60 and 65 versus ≤60; and a strongly significant association with tumor location (Table 1).