However, some enhancing effects on the humoral immune status associated with certain dietary interventions (i.e., B. breve M-16V on systemic IgM) are in line with our results related to the supplementation with B. breve M-16V in the previous study (43) and those derived from other probiotics such as LGG or Lactobacillus acidophilus NCFM, which increased IgM in pigs and infants after this type of infection (62–64). Here, CD40LG is linked to infection.