Tumor PD-L1 expression was significantly associated with LNM; diffusely PD-L1-positive tumors had higher odds of LNM in comparison to tumors with marginal PD-L1 expression only [OR 4.16, p < 0.01] and to tumors with combined negative/margin PD-L1 expression (OR 3.28, p < 0.01). The gene discussed is CD274; the disease is neoplasm.