While for VEGF (rs3025039, rs10434, rs1570360, rs2010963, and rs833061), HIF1α (rs11549465 and rs11549467), HRAS-rs12628 and eNOS-rs1799983 polymorphisms, our meta-analysis indicated there were no significant associations between them and urogenital neoplasms susceptibility even in subgroup analysis by ethnicity, HWE status, source of controls and cancer type (multiple testing P-value according to Bonferroni correction [P < 0.05/(12 polymorphisms × 5 models)] was considered as statistically significant). This evidence concerns the gene HIF1A and cancer.