While this association did not remain significant for in-hospital mortality after adjusting for age, sex, BMI, NT-proBNP, MAP, GFR, and either urea, IL-6, and LDL cholesterol, or COPD, CKD, CM, ACS, and NYHA, the adjustment did not qualitatively change the results for 3-month mortality (Table 4). The gene discussed is NPPB; the disease is chronic kidney disease.