While primarily thought of as an hepatic enzyme that plays a major role in glucose homeostasis, G6PC is known to be dysregulated in an array of human tumor types (Abbadi et al. 2014, Guo et al. 2015) and is a target of p53 regulation (Kim et al. 2013, Zhang et al. 2014). This evidence concerns the gene G6PC1 and neoplasm.