These facts suggest that the Anthropoid primate-specific adrenal androgen-mediated tumor suppressor system enabled the harnessing of fire by primitive humans, and the consequent exposure to the carcinogens produced in heat-processed meat selected for humans with the highest circulating levels of DHEAS, and hence, optimum function of the kill switch tumor suppressor system. The gene discussed is SULT2A1; the disease is neoplasm.