Plasma protein M or paraprotein, monoclonal immunoglobulin synthesized by tumor cells, was investigated in 18 cases.2, 4, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30 The presence of the M-protein was reported in 8 case reports,14, 16, 20, 21, 23, 24, 28, 29 corresponding to 38.09%. This evidence concerns the gene MYOM2 and neoplasm.