IL-32 is involved in the pathogenesis of a number of chronic inflammatory diseases and allergic diseases including but not limited to rheumatoid arthritis (RA), chronic obstructive pulmonary disease (COPD), COPD exacerbation, inflammatory bowel disease (IBD), chronic rhinosinusitis and asthma (Table 1) [1, 6, 21, 33, 34]. Here, IL32 is linked to asthma.