ANGPTL8 and coronary artery disorder: In this study, we found that circulating ANGPTL8 levels is higher in men compared with women in the control group (492.73 ± 148.42 vs 361.38 ± 118.44 pg/ml, P = 0.002), while there were no differences in the levels of circulating ANGPTL8 between the two genders in patients with CAD (667.51 ± 238.24 vs 658.93 ± 273.90 pg/ml, P = 0.912).