Many studies have confirmed the loss of epithelial markers (e.g. E-cadherin) and gain of mesenchymal markers (e.g. vimentin) in chronic rhinosinusitis epithelial layers and the pathogenesis of nasal polyps, which shows that there are correlations between EMT and chronic rhinosinusitis with or without nasal polyps [2, 7, 17]. Here, VIM is linked to chronic rhinosinusitis.