LAT and breast cancer: These analyses confirmed aberrantly high expression of LAT1 (SLC7A5) and its heterodimeric heavy chain, SLC3A2, in cell lines (Fig. 4b, Additional file 2: Figure S2A) and clinical samples (Fig. 4c, Additional file 2: Figure S2B), with significantly higher expression in more proliferative breast cancer subtypes (Fig. 4c, Additional file 2: Figure S2C, Additional file 1: Table S2; basal, claudin-low, HER2; p < 0.0001, Kruskal-Wallis test).