C. elegans doesn’t possess specialized immune cells per se, but injury and bacterial or fungal infections induce an innate immune response that includes the production of antimicrobial peptides (AMPs), especially, in the case of fungal infection of the epidermis, members of the NLP (neuropeptide-like protein) and the CNC (caenacin) families (Engelmann and Pujol, 2010). The gene discussed is PRKAR1A; the disease is fungal infectious disease.