SNCG which contributes to immunosuppressive effects via the inhibition of DC differentiation and activation is shown to promote cell growth and motility leading to cancer metastasis and invasiveness.21 Indoleamine 2,3‐dioxygenase 2 (IDO2), a newly discovered enzyme, is able to catabolize tryptophan into kynurenine, therefore highly expressed in various types of cancer cells, as well as immune cells. This evidence concerns the gene IDO2 and cancer.