In addition, because Int is less active than are other SSRs like Flp and Cre [58] and (unpublished data), its weaker recombination activity leads to the formation of only a small amount of the active hTERT-attB-dta recombination product in LLC-Kat cancer cells (Figure 1) which does not affect the normal TERT balance such that no excess of TERT suppressors is needed. Here, INTU is linked to cancer.