As immune disease-related genes, MYD88 (81.4%) and BCL10 (25.9%) in NF-ĸB signaling, CD79B (59.2%), PAX5 (22.2%), and BCR (7.4%) in B-cell development, and MYH11 (25.9%), RUNX1 (7.4%), and TET2 (7.4%) in leukemia were observed (Figure 3). The gene discussed is TET2; the disease is leukemia.