KRT20 and colorectal carcinoma: Applying a multivariate analysis for all variables showing a significant correlation to survival in the univariate analysis, we could prove that CK20 mRNA expression above or below the cut-off in CRC patients represents an independent prognostic marker in the entire cohort (UICC stages I-IV) for the OS (HR 2.49; 95% CI 1.77 – 3.49; P<0.001) and DFS (HR 2.34; 95% CI 1.69 – 3.22; P<0.001) (Table 3, upper panel).