ATXN3 and Cirrhosis: Next, we investigated the effects of AT3 rs8021276 polymorphism on the amount of AFB1-DNA adducts in the liver tissues with cirrhosis using comparative enzyme-linked immunosorbent assay and found that this polymorphism can modify the amount of DNA adducts (means ± S.D., 1.51 ± 1.23 μmol/mol DNA for rs8021276-AA, 2.09 ± 1.18 μmol/mol DNA for rs8021276-AG, and 3.92 ± 1.81 μmol/mol DNA for rs8021276-GG, respectively, P = 5.61 × 10-4) (Figure 1F).