The Vγ9Vδ2 subset of γδ T cells is uniquely adapted for tumor immunity through: non-reliance on MHC expression, relative insensitivity to PD-1 inhibition, potent and broad tumor cytotoxicity, low contribution to IL-17A production, activation of NK cytotoxicity, and costimulation of NK for killing of mature (inflammatory) dendritic cells. This evidence concerns the gene IL17A and neoplasm.