The role of this pathway in cancer transformation and growth is confirmed by the fact that FGFR1 inhibitors attenuate both LMP1-mediated aerobic glycolysis, reducing lactate dehydrogenase A (LDHA) phosphorylation and activity in nasopharyngeal epithelial cells, and cellular transformation, proliferation, migration, and invasion (Kelleher et al., 2013; Lo et al., 2015). Here, LDHA is linked to cancer.