To obtain more supporting evidence to validate our findings, we analysed the correlation between MDR1 and WBP2 using TCGA data set, which contained 1090 breast cancer patients and result showed that there was a slight positive relativity between MDR1 (ABCB1) and WBP2 (p = 0.050) (Fig. S4A). The gene discussed is ABCB1; the disease is breast cancer.