VEGFA and glomerulosclerosis: In other words, increased antiangiogenic factors can mimic VEGF-A deficiency, and may promote glomerular endothelial injury observed in podocyte-specific VEGF-A deficient mice, possibly leading to glomerulosclerosis, and peritubular capillary loss seen in tubule-specific VEGF-A knockout mice, resulting in tubulointerstitial fibrosis.