Here, we synthesized a mixture containing equal amounts of the 3R, 7R, 11R- and the 3S, 7R, 11R-isomers in order to evaluate the in vitro immunomodulatory effects of nPA on IFN-γ production by T-cells, to address the potential for prevention of autoimmune disease. The gene discussed is IFNG; the disease is autoimmune disease.