According to this, the Acute Liver Failure Study Group of the University of Texas Southwestern Medical Centre (UTSWMC) defined criteria for acute liver injury in the absence of measurable hepatic encephalopathy or non-acetaminophen aetiology as acute hepatic illness of < 26 weeks, INR ≥ 2.0, ALT of ≥350 U/I, and total bilirubin concentration of ≥3.0 mg/dl [26]. This evidence concerns the gene GPT and acute liver failure.