On the one hand, Gal-8 has a pro-apoptotic effect on immature CD4highCD8high thymocytes [39] and causes phosphatidylserine exposure on activated Th17 and promyelocytic tumor (HL60) cells as well as synovial fluid cells of rheumatoid arthritis patients [40–42]. The gene discussed is LGALS8; the disease is rheumatoid arthritis.