MMP14 and thyroid gland carcinoma: Therefore, to investigate if reciprocal levels of PROX1 and MMP14 would be observed also in thyroid cancer, we performed double-staining IHC for PROX1 and MMP14 on a tissue microarray (TMA) including 57 specimens of which 44 originated from different thyroid cancers and 13 from benign hyperplasias.