NFKB1 and cancer: Cancer development in the presence of chronic inflammation involves the constant presence of activated oncogenes and transcriptional factors such as nuclear factor-κB (NF-κB), signal transducer and activator of transcription 3, activator protein 1, hypoxia-inducible factor 1α, forkhead box protein M1, peroxisome proliferator associated receptor γ, Wnt/β-catenin, c-Met (hepatocyte growth factor receptor), and hedgehog (HH/GLI) [2,4,70,71,79–81].