Based on our search of PubMed (from January 1960 to July 2018; search terms: “Alpha-fetoprotein”, “clear cell”, “ovarian cancer”; https://www.ncbi.nlm.nih.gov/pubmed/?term=Alpha-fetoprotein%2C+clear+cell%2C+ovarian+cancer), there are a few cases of AFP-producing clear cell type EOC available in the literature [1–3]. This evidence concerns the gene AFP and ovarian cancer.