FGFR3 and nasopharyngeal carcinoma: FGFR3 is found to be mutated or rearranged in 11–14% of HPV(+) HNSCC (4/36 cases) [50,76] vs. 0% of HPV(−) HNSCC (0/243 cases; TCGA), and in 1.8% of EBV(+) NPC (2/111 cases) [81].