In conclusion, among patients with stage 3–4 diabetic CKD, higher baseline HbA1c levels correlated with higher risks for ESRD, all-cause mortality, and composite outcomes (CV events and all-cause mortality) in patients with Hb ≥ 10 g/dL, whereas the association did not exist in those with Hb < 10 g/dL. Here, GSTM1 is linked to chronic kidney disease.