In support of this, HTyr has been shown to induce the expression of EGR1 in human promyelocytic leukemia cultured cells [116] and, the oral administration of sulforaphane or SFGluc promoted the appearance of derived metabolites and the induction of HMOX1 in the breast tissue of rats and women [117]. The gene discussed is EGR1; the disease is acute promyelocytic leukemia.