Also, Akbarzadeh S and his colleagues reported that there were significant increases in serum levels of insulin and HOMA-IR in the PCOS group compared to the control group; they also reported that in PCOS women with normal BMI, there is no significant difference in the levels of omentin and vaspin that are associated with insulin resistance [40]. The gene discussed is ITLN1; the disease is polycystic ovary syndrome.