EZH2 and neoplasm: Next, we analyzed the enrichment of H3K27me3 and Ezh2 at the promoters of NGFR, WT1 and MME in these cell lines and human NSCs, and observed that H3K27me3 and Ezh2 were enriched at the promoters of WT1 promoter more than other two gene promoters in all these tumor lines tested (Figure 4—figure supplement 1B and C).