Peptide vaccines developed from LAAs, such as Wilms’ tumor 1 (WT1) antigen, Proteinase-3 (PR3) peptide, preferentially expressed antigens of melanoma (PRAME) and receptors for hyaluronic acid-mediated motility (RHAMM), have been explored and/or are under clinical investigation for the treatment of AML [19,20,21,22]. This evidence concerns the gene PRTN3 and melanoma.