Moreover, granuloma formation around L. sigmodontis worms in BALB/c mice is mainly composed of neutrophils in the later stages of infection (Al-Qaoud et al. 2000; Attout et al. 2008) and RANTES secretion was shown to be more critical for eosinophil recruitment at later time points during allergic airway inflammation (Gonzalo et al. 1998). This evidence concerns the gene CCL5 and infection.