While there was no significant differences in postoperative suPAR concentration between moderately and poorly differentiated tumors or KRAS mutated and non-mutated patients (Supplementary Figure 2B and 2C), CRLM patients with right-sided primary CRC showed significantly elevated suPAR levels compared to left-sided CRC patients (Supplementary Figure 2D). This evidence concerns the gene KRAS and colorectal carcinoma.