There was no significant difference in HbA1c levels between the four diabetic groups: diabetes (DM), diabetes treated with the LOXL2 inhibitor PXS-S2B (DM + LOXL2i), diabetes treated with telmisartan (DM + Telmi) and diabetes treated with both drugs (DM + LOXL2i + Telmi). This evidence concerns the gene LOXL2 and diabetes mellitus.