The most significantly biological functions associated with FANCC were cancer (p=4.39×10 -02– 5.93X10 -14, 30 metabolites), inflammatory disease (p=3.67×X10 -02–3.39×10 -07, 7 metabolites) gastrointestinal disease ( p=4.39×10 -02– 5.93×10 -14, 28 metabolites), organismal injury and abnormalities (p=4.4×10 -02– 3.39×10 -07, 7 metabolites) amino acid metabolism (p=3.89×10 -02 – 2.43×10 -10, 21 metabolites) and liver inflammation/ Hepatitis (p=3.03×10 -01 – 3.67×10 -02 , 3 metabolites). The gene discussed is FANCC; the disease is gastrointestinal disease.