MYBPC3 and hypertrophic cardiomyopathy: Moreover, dominant mutations in slow MyBP-C have been linked to the development of distal arthrogryposis (Geist and Kontrogianni-Konstantopoulos, 2016), while cMyBP-C mutations have been reported in hypertrophic cardiomyopathy (HCM), DCM and left ventricular non-compaction (Carrier et al., 2015).