Transient receptor potential (TRP) channels such as TRPA1 and TRPV1 are implicated in both the pain (Cui et al., 2014; Pabbidi et al., 2008; Wei et al., 2009) and neuronal damage in diabetic neuropathy (Koivisto et al., 2012). The gene discussed is TRPA1; the disease is diabetic neuropathy.