The pain and neuronal damage in diabetic neuropathy are related to the decrease in expression of vascular endothelial growth factor-A (VEGF-A) (Jerić et al., 2017; Pawson et al., 2010), a family of growth factors with effects on both vascular and neuronal systems (Carmeliet and Storkebaum, 2002). This evidence concerns the gene VEGFA and diabetic neuropathy.