As such, we performed RNA sequencing of brain and blood from the hemizygous MJD84.2 mouse model of SCA3, which ubiquitously expresses the full human ATXN3 gene with 76–77 CAGs [16] and gene expression analysis was performed in 4 different regions of the brain. This evidence concerns the gene ATXN3 and Spinocerebellar ataxia type 3.