Ceramide has an apoptosis induction role in cancer cells through activation of various pro‐apoptotic molecules, such as Bcl‐2 nineteen‐kilodalton interacting protein 3 (BNIP3), a tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) 55, and death‐associated protein kinase 2 (DAPK2) 56. The gene discussed is DAPK2; the disease is cancer.