NF2 and Miyoshi myopathy: Given the low penetrance in our model, as reported before (≈10% in C57-NF2+/− mice [12]), i.e. 3/30 in the C57-NF2+/-CR−/− mouse group and 2/18 in the C57-NF2+/-CR+/+ mouse group in this study, the small number of confined MM cases doesn’t allow to directly link Calb2 genotype to MM-caused mortality.