TNFAIP8 and prostate cancer: Because TNFAIP8 is a TNFα-inducible protein [12], we confirmed the expression and identity of TNFAIP8 isoforms by treating three prostate cancer cell lines (PC3, LNCaP, and C4-2) with TNFα and analyzing the induction of TNFAIP8 isoform proteins.