RAB11B and osteosarcoma: In addition, luciferase reporter assay illustrated the interaction between RAB11B-AS1 and the RAB11B. Most importantly, all the effects of lnc-RAB11B-AS1 were abrogated by RAB11B down-regulation, which validated that lnc-RAB11B-AS1 exerts its function in osteosarcoma via RAB11B.