For this, we wanted to explore breast cancer primary cultures that although considered non-aggressive because of their clinical staging and histological grading, they were highly inflammatory in culture, particularly of the inflammatory molecules that we have previously reported for Hs578T and MDA-MB-231 cells: G-SCF, IL-8, MMP1, GM-CSF, MCP-1 and MMP2. This evidence concerns the gene MMP1 and breast carcinoma.