SKA1 and neoplasm: After multivariate analysis, high SKA1 and SKA3 expression levels, age, tumor stage and histological grade were independent predictive factors for overall survival (hazard ration (HR) = 1.48, p = 0.0134, HR = 1.53, p = 0.0073, HR = 2.75, p < 0.0001 and HR = 1.67, p = 0.004, respectively; Table 3).